Diabetes and the Drugs to Control it Could Shorten your Life

I'm often asked, "How can I live to be 100 years old?" My answer is simple, "Just say no to prescription drugs and learn how to control insulin and blood sugar."

Why? Because the populations that live the longest are naturally highly sensitive to insulin. Conversely, those who die the youngest from conditions such as obesity, diabetes, heart disease, and even cancer are grossly insensitive to insulin or are taking a prescription drug.

In the US, the biggest threat to longevity is type II diabetes caused by high levels of blood sugar and insulin resistance. It has become a nationwide epidemic that can steal 11 to 20 years from a person's lifespan.

To curb the threat, physicians are madly prescribing anti-diabetic drugs like Avandia and Actos. With so many people using them, scientists have learned two valuable lessons about longevity.

First lesson: You cannot use these drugs to increase lifespan.

In addition to eliciting a moderate drop in blood sugar, anti-diabetic meds damage the cardiovascular system.

According to a recent study, Avandia users had a whopping 30-40% increased risk of heart attack and other heart-related adverse events (heart failure) compared to patients treated with placebo.(1) This risk is due to the drug's effect of lowering vital hemoglobin levels.

Hemoglobin is used by the body to transport oxygen throughout the entire 100,000 miles of veins, arteries, and capillaries in the adult body. Without hemoglobin, a condition known as ischemia sets in. This is a fancy term for "suffocation." Clinically, heart attack or heart failure can be the result.

The prescription drug Actos has the same mechanism of action as Avandia -- they both work to reduce insulin resistance. Not surprisingly, it also carries the same risks. Health Canada sounded the alarm about this class of drugs as early as 2001! But unfortunately, the warning has not yet reached the American public.

Commenting on this unannounced danger, the U.S. Congress stated that, "the FDA's apparently callous disregard for the safety of diabetics taking Avandia is very reminiscent of the Agency's failure to move on Vioxx when substantial safety signals first became known. Like Vioxx, Avandia may have unnecessarily risked the lives of tens of thousands of Americans."(2)

Second lesson: You can fix insulin receptors naturally to increase lifespan.

This simply means that insulin receptors found on individual cells have the ability to be "re-tuned" to the insulin message. We learned this from anti-diabetic drugs that can increase insulin sensitivity by jump starting inactive or dying cells. But this benefit from drugs doesn't outweigh the risk of heart attack. Fortunately, if a drug can do it, so can Mother Nature. This is a little-known fact in medicinal chemistry.

Mother Nature always provides the "lead" in the meticulous process of drug discovery. Meaning, before there is a man-made drug for a given ailment, there is a natural substance that will do the same thing.

In the process of designing anti-diabetic drugs, Big Pharma surveyed a myriad of natural products to find a lead compound that re-tuned the insulin receptor. Among them was a substance called corosolic acid, derived from the banaba plant(3) grown in Southeast Asia.

Corosolic acid has proven safe and effective for increasing insulin sensitivity. Remarkably, users have been shown to not only lower blood sugar and insulin levels but also melt fat and build muscle in the process. But what's really important is that by taking corosolic acid instead of anti-diabetic drugs you will lower the risk of heart attack and naturally improve insulin sensitivity. That means years may be added to your life!

Of course, lifestyle habits such as regular exercise and minimizing sugar intake are pre-requisites to the success of increasing insulin sensitivity and significantly extending your lifespan.

(You can find corosolic acid as an ingredient in several natural products sold in health food stores for glucose control and weight management.)

Shane “The People’s Chemist” Ellison has an MS in organic chemistry and has first hand experience in drug design and synthesis. He is a two-time recipient of the prestigious Howard Hughes Medical Institute Research Grant for his studies in physiology and biochemisty.
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